This seemed to fix the issues I was having getting it to run. I was running PS2 through steam and having no luck and crashing much more than usual. The simple solution is to run the game from outside of steam and run it as administrator. That seems to have taken care of the problem. I would give that a shot
EDIT: So this didn't actually work as I thought and caused problems with the mumble overlay. Currently not running the overlay to get things working